Highlight Articles in Int J Ophthalmol Vol.16 No.2 2023
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Highlight Articles in Int J Ophthalmol Vol.16 No.2 2023

  

CLINICAL RESEARCH

Nomogram for predicting non-proliferative vitreoretinopathy probability after vitrectomy in eyes with rhegmatogenous retinal detachment

Zhi-Qiang Gao, Pei-Yu Wu, Jing Zhang, Zhi-Sheng Ke, Xu-Ting Hu, Zhao-Liang Zhang, Jing-Wei Zheng, Zong-Duan Zhang, Qin-Tuo Pan

 

This study aims to identify the risk factors for postoperative proliferative vitreoretinopathy (PVR) in patients with primary rhegmatogenous retinal detachment (RRD) and develop a nomogram for predicting postoperative PVR-free probability. Totally 741 RRD patients (741 eyes) retrospectively reviewed and randomly assigned with 521 to the training set and 220 to the validation set. The results showed that preoperative PVR, silicone oil tamponade time, photocoagulation energy, retinal tear size, and hypertension are significant risk factors for postoperative PVR formation in patients with primary RRD. Based on the currently identified risk factors, a novel nomogram was constructed to predict the PVR-free probability in patients with primary RRD at 4, 5, and 6mo after surgery. This nomogram, with its good discrimination and calibration, will be beneficial for personalized PVR prediction and facilitating clinical decision-making during follow-up.

 

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Nomogram图预测孔源性视网膜脱离患者玻璃体切除术后非增殖性玻璃体视网膜病变的概率

 

该研究旨在确定原发性孔源性视网膜脱离(RRD)患者术后增殖性玻璃体视网膜病变(PVR)的危险因素,并建立预测术后无PVR概率的Nomogram图。作者对741例(741眼)RRD患者进行了回顾性分析,并随机分为训练集(521眼)和验证集(220眼)。研究结果表明,术前PVR、硅油填充时间、光凝能量、视网膜裂孔大小和高血压是原发性RRD患者术后PVR形成的重要危险因素。基于目前确定的风险因素,构建一个新的Nomogram图以预测原发性RRD患者在术后456个月无PVR的概率。该Nomogram图具有良好的区分能力和校准度,将有助于个性化PVR预测及随访期间的临床决策。

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CLINICAL RESEARCH

Should ocular Demodex be checked and treated in refractory keratitis patients without blepharitis

Ying-Ying Gao, Ting Wang, Yu-Ting Jiang, Ming-Jun Yang, Xiu-Hai Lu, Ling Zheng, Shu-Ting Wang, Wei-Yun Shi

 

This study evaluated the correlation between Demodex infestation and keratitis, and to assess demodicosis using a simple approach. Before treatment, Demodex tails were found in all patients (40/40, 100%), compared to 53% (42/80) of the controls. The growth of Staphylococcus was revealed in nine patients who did not react to antibiotic eye drops prior to the tea tree oil ointment (TTOO) treatment. Patients’ signs and symptoms got resolved after the lid scrub with TTOO. In conclusion, ocular Demodex needs to be checked and treated in refractory keratitis patients with or without blepharitis. A slit-lamp illumination under high magnification favors the judgment of the severity of Demodex infestation.

 

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无睑缘炎的难治性角膜炎患者是否应检查和治疗眼部蠕形螨?

 

该研究评估了蠕形螨感染与角膜炎之间的相关性,并使用简单的方法评估蠕形螨感染。治疗前,在40100%)例难治性角膜炎患者和4253%)例健康对照中发现蠕形螨尾蚴。在茶树油软膏治疗前对抗生素滴眼液无反应的9例患者中发现葡萄球菌生长。用茶树油软膏擦洗眼睑后,患者体征和症状均得到缓解。总之,无论是否有睑缘炎的难治性角膜炎患者,需要检查和治疗眼睛蠕形螨。高倍率裂隙灯检查有利于蠕形螨感染严重程度的判断。

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REVIEW

Regional chemotherapy for uveal melanoma liver metastases

Yang-Xu Tao, Hao-Wen Li, Jing-Ting Luo, Yang Li, Wen-Bin Wei

 

Chemotherapy remains an important approach for the treatment of liver metastases from uveal melanoma (UM). Compared with systemic chemotherapy, regional chemotherapy has similar efficacy and fewer systemic adverse effects. Regional chemotherapy for UM liver metastases includes hepatic artery infusion (HAI), transarterial chemoembolization (TACE), and isolated hepatic perfusion (IHP). In this review, the authors aim to examine the efficacy of regional chemotherapy and compare HAI, TACE, and IHP in terms of overall survival (OS). The three approaches showed no obvious di?erence in OS results.

 

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葡萄膜黑色素瘤肝转移的局部化疗

 

化疗仍然是治疗葡萄膜黑色素瘤(UM)肝转移的重要方法。与全身化疗相比,局部化疗疗效相近,全身不良反应较少。UM肝转移的局部化疗包括肝动脉灌注(HAI)、经动脉化疗栓塞术(TACE)和隔离肝脏灌注(IHP)。该综述中,作者调查了局部化疗的疗效,并比较HAITACEIHP在生存率方面的差异,发现三种方法的生存率无明显差异。

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Published date:2023-02-03Click:

Editors-in-Chief: Yan-Nian Hui and Peter Wiedemann

Established in April, 2008

ISSN 2222-3959 print

ISSN 2227-4898 online

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