Highlight Articles in Int J Ophthalmol Vol.15 No.6 2022
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Highlight Articles in Int J Ophthalmol Vol.15 No.6 2022



Intraocular lens removal or not during vitrectomy for acute infectious endophthalmitis after cataract surgery

Yan-Nian Hui


At present, the incidence of infectious endophthalmitis after cataract surgery has been significantly reduced, but it is still a serious complication. Removal or not of the intraocular lens (IOL) during vitrectomy in cases with a moderate or severe inflammation is controversial. In order to call upon more attention, we discuss this controversial situation in this issue. With recent advanced vitrectomy techniques, and critical measures for management of risk factors related to occurrence of infection, IOL remaining during timely vitrectomy for acute endophthalmitis can possibly be safe and effective in selected cases.






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Evaluation of nintedanib as a new postoperative antiscarring agent in experimental extraocular muscle surgery

Gozde Bicaklioglu, Dilara Pirhan, Yusufhan Yazir, Gokhan Duruksu, Selenay Furat Rencber, Nursen Yuksel


This study aimed to investigate the efficacy of nintedanib on reducing postoperative inflammation, fibrosis and adhesion formation following extraocular muscle surgery in rabbits in comparison with triamcinolone acetonide (TA). It turns that conjunctival and scleral inflammation in TA and nintedanib groups were significantly reduced compared to saline group. Nintedanib appears to attenuate postoperative inflammation and fibrosis after extraocular muscle surgery. But TA showed its main effect as an anti-inflammatory agent, its antifibrotic effect was weaker. Nintedanib may be a safer and stronger alternative agent in extraocular muscle surgery when compared to steroids. Although the researcher think that nintedanib may have a role in improvement of extraocular muscle surgery success, further investigations are needed to determine long term toxic effects and duration, application and dosage of nintedanib treatment.






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Etiology, pathogenesis, and diagnosis of neovascular glaucoma

Dan C?lug?ru, Mihai C?lug?ru


Neovascular glaucoma is a secondary glaucoma that is most frequently caused by severe retinal ischemia. The most common diseases responsible for the development of neovascular glaucoma are diabetic retinopathy, ischemic central retinal vein occlusion, and ocular ischemic syndrome. Uncommon causes include ocular radiation, ocular tumors, uveitis and other miscellaneous conditions. Vascular endothelial growth factor is an important and likely predominant protein involved in the pathogenesis of intraocular neovascularization and neovascular glaucoma. The evolution of clinical and histopathological changes from predisposing conditions to the occurrence of rubeosis iridis and neovascular glaucoma is divided into four stages: prerubeosis, preglaucoma, open angle glaucoma, and angle-closure glaucoma.






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Timely vitrectomy without intraocular lens removal for acute endophthalmitis after cataract surgery

Hai-Xia Guo, Ruo-Tian Xie, Yun Wang, Cai-Yun You, Yuan-Yuan Liu, Xiang-Da Meng, Jin-Guo Yu, Hua Yan


Acute post-cataract endophthalmitis remains the most serious complication after cataract surgeries. IOL removal decreased uncorrected and/or best-corrected visual acuity and left the patients unsatisfied with the visual results, which most likely led to postoperative medical dissension during vitrectomy. By now, there are few reports on the effect of vitrectomy for postoperative pseudophakic endophthalmitis without IOL removal, therefore, the clinical feature, causative organism, and effect of vitrectomy and silicone oil tamponade without IOL removal on the treatment of acute-onset endophthalmitis after cataract surgery are reported here using a small case series. In conclusion, under systemic antibiotic treatment and timely diagnosis, vitrectomy and silicone oil tamponade without IOL removal is a safe and effective method for acute-onset endophthalmitis after cataract surgery.






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Published date:2022-06-01Click:

Editors-in-Chief: Yan-Nian Hui and Peter Wiedemann

Established in April, 2008

ISSN 2222-3959 print

ISSN 2227-4898 online

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