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Highlight Articles in Int J Ophthalmol Vol.16 No.1 2023
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Highlight Articles in Int J Ophthalmol Vol.16 No.1 2023

 

COVID-19 and Ophthalmology

Visual perception alterations in COVID-19: a preliminary study

María Begoña Coco-Martín, Luis Leal-Vega, Irene Alcoceba-Herrero, Ainhoa Molina-Martín, Dolores de-Fez, María José Luque, Carlos Dueñas-Gutiérrez, Juan Francisco Arenillas-Lara, David P. Piñero

 

This study compared the visual perception (color and chromatic-achromatic contrast vision) of a small cohort of COVID-19 patients at the time of infection and after 6mo with that of a healthy population matched for sex and age. A total of 25 patients (9 females, 16 males, mean age: 54±10y) with COVID-19 hospitalized were recruited for this preliminary study. Visual perception, as determined by monocular measurement of contrast sensitivity function (CSF) and color vision was assessed in each patient using the Optopad test. The evidence show that visual perception may be impaired in COVID-19, even when the infection has passed. Although further research is needed to determine the precise causes of this finding, analysis of CSF and color vision could provide valuable information on the visual impact of COVID-19.

 

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COVID-19患者视觉感知改变的初步研究

 

该研究比较了COVID-19患者在感染时和感染6个月后视觉感知功能(彩色和彩色-非彩色对比视觉)的改变。研究共招募了25COVID-19住院患者(9例,男16例,平均年龄54±10y)。使用Optopad测试评估每位患者的视觉感知(单眼对比敏感度函数测量和色觉评估)。结果表明即使感染已经过去,COVID-19患者的视觉感知受损可能仍然存在。虽然需要进一步研究来确定这一发现的确切原因,但对比敏感度函数和色觉分析有助于评估COVID-19引起的视觉损伤。

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BASIC RESEARCH

Intravitreal slow-release dexamethasone alleviates traumatic proliferative vitreoretinopathy by inhibiting persistent inflammation and Müller cell gliosis in rabbits

Yi-Ming Zhao, Rong-Sha Sun, Fang Duan, Fang-Yu Wang, Yu-Jie Li, Xiao-Bing Qian, Jie-Ting Zeng, Yao Yang, Xiao-Feng Lin

 

This study aims to evaluate the effects of intravitreal slow-release dexamethasone (Ozurdex) on traumatic proliferative vitreoretinopathy (PVR) and Müller cell gliosis and preliminarily explored the possible inflammatory mechanism in a rabbit model induced by penetrating ocular trauma. The findings confirmed the beneficial effect of Ozurdex on traumatic PVR by inhibiting the chronic inflammation response and Müller cell gliosis in rabbits after penetrating ocular injury. In summary, Ozurdex provides a potential therapeutic option for traumatic PVR.

 

对照译文

地塞米松玻璃体缓释植入物通过抑制持续性炎症和Müller细胞胶质增生减轻兔外伤性增生性玻璃体视网膜病变

 

该研究旨在评估地塞米松玻璃体缓释植入物(Ozurdex)对兔外伤性增生性玻璃体视网膜病变和Müller细胞胶质增生的影响,并初步探讨了穿透性眼外伤诱导的兔模型中可能的炎症机制。其研究结果证实了Ozurdex通过抑制兔穿透性眼损伤后的慢性炎症反应和Müller细胞胶质增生对外伤性增生性玻璃体视网膜病变的有益作用。总之,Ozurdex为创伤性增生性玻璃体视网膜病变提供了一种潜在的治疗选择。

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CLINICAL RESEARCH

Comparison of success rate and intraocular pressure spikes between selective laser trabeculoplasty and micropulse laser trabeculoplasty in African American and Hispanic patients

Alexander Z Robin, Palwasha Syar, Dana Darwish, Catherine Thomas, N.M. Pfahler, Agni Kakouri, Thomas Patrianakos, Michael Giovingo

 

Laser trabeculoplasty (LT) is a mainstay of treatment for the management of open-angle glaucoma (OAG). The aim of this study is to demonstrate the efficacy and safety of micropulse laser trabeculoplasty (MLT) in a large cohort that is more representative of the demographic of patients with OAGs. MLT has a significantly lower incidence of pressure spikes and a similar treatment failure rate at 1-year post-procedure, demonstrating that it is a reasonable alternative compared to selective laser trabeculoplasty (SLT).

 

对照译文

选择性激光小梁成形术和微脉冲激光小梁成型术在非裔美国人和西班牙裔患者的成功率和眼压峰值比较

 

激光小梁成形术是治疗开角型青光眼(OAG)的主要方法。该研究为大样本队列研究,研究对象为具有代表性的OAG患者人群,探讨微脉冲激光小梁成形术(MLT)的有效性和安全性。MLT术后1年眼压峰值发生率明显较低,治疗失败率相似,与选择性激光小梁成形术(SLT)相比,MLT是一种合理的选择。

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Published date:2022-12-30Click:

Editors-in-Chief: Yan-Nian Hui and Peter Wiedemann

Established in April, 2008

ISSN 2222-3959 print

ISSN 2227-4898 online

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