Highlight Articles in Int J Ophthalmol Vol.16 No.2 2023
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Highlight Articles in Int J Ophthalmol Vol.16 No.2 2023



Nomogram for predicting non-proliferative vitreoretinopathy probability after vitrectomy in eyes with rhegmatogenous retinal detachment

Zhi-Qiang Gao, Pei-Yu Wu, Jing Zhang, Zhi-Sheng Ke, Xu-Ting Hu, Zhao-Liang Zhang, Jing-Wei Zheng, Zong-Duan Zhang, Qin-Tuo Pan


This study aims to identify the risk factors for postoperative proliferative vitreoretinopathy (PVR) in patients with primary rhegmatogenous retinal detachment (RRD) and develop a nomogram for predicting postoperative PVR-free probability. Totally 741 RRD patients (741 eyes) retrospectively reviewed and randomly assigned with 521 to the training set and 220 to the validation set. The results showed that preoperative PVR, silicone oil tamponade time, photocoagulation energy, retinal tear size, and hypertension are significant risk factors for postoperative PVR formation in patients with primary RRD. Based on the currently identified risk factors, a novel nomogram was constructed to predict the PVR-free probability in patients with primary RRD at 4, 5, and 6mo after surgery. This nomogram, with its good discrimination and calibration, will be beneficial for personalized PVR prediction and facilitating clinical decision-making during follow-up.






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Should ocular Demodex be checked and treated in refractory keratitis patients without blepharitis

Ying-Ying Gao, Ting Wang, Yu-Ting Jiang, Ming-Jun Yang, Xiu-Hai Lu, Ling Zheng, Shu-Ting Wang, Wei-Yun Shi


This study evaluated the correlation between Demodex infestation and keratitis, and to assess demodicosis using a simple approach. Before treatment, Demodex tails were found in all patients (40/40, 100%), compared to 53% (42/80) of the controls. The growth of Staphylococcus was revealed in nine patients who did not react to antibiotic eye drops prior to the tea tree oil ointment (TTOO) treatment. Patients’ signs and symptoms got resolved after the lid scrub with TTOO. In conclusion, ocular Demodex needs to be checked and treated in refractory keratitis patients with or without blepharitis. A slit-lamp illumination under high magnification favors the judgment of the severity of Demodex infestation.






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Regional chemotherapy for uveal melanoma liver metastases

Yang-Xu Tao, Hao-Wen Li, Jing-Ting Luo, Yang Li, Wen-Bin Wei


Chemotherapy remains an important approach for the treatment of liver metastases from uveal melanoma (UM). Compared with systemic chemotherapy, regional chemotherapy has similar efficacy and fewer systemic adverse effects. Regional chemotherapy for UM liver metastases includes hepatic artery infusion (HAI), transarterial chemoembolization (TACE), and isolated hepatic perfusion (IHP). In this review, the authors aim to examine the efficacy of regional chemotherapy and compare HAI, TACE, and IHP in terms of overall survival (OS). The three approaches showed no obvious di?erence in OS results.






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Published date:2023-02-03Click:

Editors-in-Chief: Yan-Nian Hui and Peter Wiedemann

Established in April, 2008

ISSN 2222-3959 print

ISSN 2227-4898 online

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