目的：探讨行超乳手术患者前房参数的变化及影响眼压变化的因素。

方法：本文对82例105眼行白内障手术的非青光眼患者临床资料进行了纵向分析。研究术后3wk内前房参数、白内障分级、人口统计学资料和眼压变化之间的关系。并评估眼压-前房深度(PD)比率与此期间眼压变化之间的关系。

结果：纳入的82例患者平均年龄为60.1±7.8岁。术前平均IOP为15.06±3.36 mmHg； 术后1d增加到15.75±4.21 mmHg(P=0.20)。在多因素模型中，与术前值比较，术后21±5d平均IOP变化为-1.715 mmHg(95% CI： -2.795， -0.636)。前房深度(ACD)、眼轴长度、年龄、性别和白内障分级与眼压变化无显著相关。PD比率每增加一个单位，平均眼压就增加1.289 mmHg(95% CI： 0.906， 1.671)。对术前PD值进行校正后，ACD、眼轴长度、颞侧房角与平均IOP无显著相关性。

结论：PD比值是影响术后3wk眼压变化的单一重要因素。

METHODS: It was a longitudinal analysis of secondary clinical data collected from 105 non-glaucomatous eyes(of 82 patients)undergoing a cataract surgery. We studied the association between anterior chamber parameters, grade of cataract, demographics, and changes in the IOP over a period of 3wk. We also evaluated the association between the pressure-depth(PD)ratio and changes in the IOP during this time.

RESULTS: The mean age [standard deviation(SD)] of the 82 patients was 60.1(7.8)years. The mean SD IOP was 15.06(3.36)mmHg pre-operatively; it increased to 15.75(4.21)mmHg on day one(P=0.20). In the multifactorial models, the mean IOP was -1.715 \〖95% confidence intervals(CI): -2.795, -0.636\〗 mmHg on day 21(±5)compared with the pre-operative values. The anterior chamber depth(ACD), axial length, age, sex, and grade of cataract were not significantly associated with changes in the IOP. Each unit increase in the PD ratio was associated with an increase in the mean IOP by 1.289 mmHg(95% CI: 0.906, 1.671). After adjusting for pre-operative PD ratio, none of the other variables(ACD, axial length, temporal angle)were significantly associated with changes in mean IOP.

CONCLUSION: The PD ratio was the single most important factor associated with the changes in post-operative IOP over 3wk post surgery.