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[摘要]
目的：研究正常人群黄斑区神经节细胞复合体(mGCC)厚度的对称性，确定双眼mGCC厚度差值的临界点。
方法：横断面研究。采用光学相干断层扫描技术(OCT)检测236例472眼自愿接受检查的健康志愿者双眼mGCC厚度，分析双眼mGCC厚度的差异及相关性，计算双眼mGCC厚度差值的临界点。
结果：本组研究对象右眼平均mGCC厚度为91.99±6.61μm，左眼为91.75±9.93μm； 右眼上方和下方mGCC厚度分别为92.32±6.66、91.27±8.87μm，左眼分别为92.05±6.55、91.51±6.76μm，双眼各区域mGCC厚度均相当。双眼平均mGCC厚度差值P2.5、P97.5分别为-4.82、4.36μm，上方mGCC厚度差值分别为-5.79、6.42μm，下方mGCC厚度差值分别为-7.21、6.28μm。双眼对应区域mGCC厚度均具有较强相关性。
结论：正常人双眼mGCC厚度对称，当双眼mGCC厚度差值超过正常范围时，可认为呈不对称状态，需要警惕青光眼的发生。
[Key word]
[Abstract]
AIM: To investigate interocular differences in macular ganglion cell complex(mGCC)thickness in normal healthy subjects, and to determine cutoffs for interocular differences in mGCC thickness in normal healthy subjects.
METHODS: This was a cross-sectional study. mGCC thickness were measured in 236 healthy volunteers(472 eyes)using optical coherence tomography(OCT). The differences and the relationships of mGCC thickness between right and left eyes were analyzed.
RESULTS: For the right eyes, the mean average mGCC thickness was 91.99±6.61μm, and for the left, 91.75±9.93μm, with no significant difference. The mean mGCC thickness among superior and inferior in the right eye were 92.32±6.66μm and 91.27±8.87μm, respectively. The mean mGCC thickness among superior and inferior in the left eye were 92.05±6.55 and 91.51±6.76μm, respectively. It is comparable between the two eyes at different area. The P2.5 and P97.5 percentiles of interocular difference for mean average mGCC thickness were -4.82μm and 4.36μm, for superior mGCC thickness, -5.79μm and 6.42μm, and for inferior mGCC thickness, -7.21μm and 6.28μm. There was a strong correlation in the corresponding area between the right and left eyes for the mGCC thickness.
CONCLUSION: mGCC thickness shows significant interocular symmetry in normal subjects. Interocular difference exceeding the normal limits should be considered significantly asymmetrical, and may be indicative of glaucoma.
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