目的：探讨基于CASIA2 OCT的NK和KS公式预测后房型有晶状体眼人工晶状体植入术(ICL)后拱高的准确性和一致性。方法：回顾性病例研究。选取鲁南眼科医院屈光手术中心2022年10月至2023年10月植入ICL矫正中高度近视患者85例170眼。手术前行UBM、角膜内皮、验光、眼压、眼底、角膜地形图等常规检查，符合ICL手术适应证，并按常规方法根据角膜直径和前方深度等参数，选择推荐的晶状体尺寸。手术前采用CAISA2 OCT检查，获得NK和KS公式预测的相应尺寸和预测拱高值。分析手术后1 wk，1、3、6 mo实际拱高值与NK、KS公式的预测拱高值的差异性和一致性。采用配对t检验分析NK、KS公式预测拱高值和术后各时间点实际拱高值差异。NK、KS公式预测拱高值和各时间点实测拱高值的一致性比较采用Bland-Altman分析。采用多元线性回归分析实际拱高与眼前节各参数之间的相关性。结果：NK公式预测值和术后1、3、6 mo实际拱高值比较有差异(均P<0.05)，但与术后1 wk实际拱高值比较无差异(P=0.340)。KS公式预测值和术后6 mo的实际拱高值比较有差异(P<0.05)。晶状体矢高和植入晶状体型号是术后6 mo拱高值的影响因素(均P<0.05)。NK公式和KS公式的拱高预测值均与术后6 mo的实际拱高值一致性最高。结论：CASIA2 OCT的NK和KS两种公式预测术后拱高与术后6 mo时的实际拱高一致性最高。这两个公式都可以作为晶状体型号选择的有效参考。

AIM: To explore the accuracy and consistency of predicting postoperative vault in implantable collamer lens(ICL)surgery based on the NK and KS formulas of CASIA2 OCT.METHODS: Retrospective case study. The study included 85 patients(170 eyes)who underwent ICL implantation for the correction of moderate to high myopia at the Refractive Surgery Center of Lunan Eye Hospital from October 2022 to October 2023. Routine examinations including ultrasound biomicroscopy(UBM), corneal endothelium assessment, optometry, intraocular pressure measurement, fundus examination, and corneal topography were performed. Patients who met the indications for ICL surgery were selected, and the recommended lens size was determined based on parameters such as corneal diameter and anterior chamber depth using standard methods. A CASIA2 OCT examination was used to obtain the corresponding lens size and predicted vault using the NK and KS formulas. The differences and consistency between the predicted vault by NK and KS formulas and the actual vault at 1 wk, 1, 3, and 6 mo postoperatively were analyzed. Paired t-tests were used to analyze the differences between the predicted vault by NK and KS formulas and the actual vault at each postoperative time point. The consistency between the predicted vault by NK and KS formulas and the actual vault at each time point was assessed using Bland-Altman analysis. Multivariate linear regression was used to analyze the correlation between actual vault and various anterior segment parameters.RESULTS: The NK formula showed statistically significant differences between the predicted values and the actual vault at 1, 3, and 6 mo postoperatively(all P<0.05), but no statistically significant difference was observed compared to the actual vault at 1 wk postoperatively(P=0.340). The KS formula demonstrated a statistically significant difference between the predicted values and the actual vault measured at 6 mo postoperatively(P<0.05). The lens vector height and lens model were influcing facotrs for the vault at 6 mo postoperatively(all P<0.05). Both the NK formula and KS formula had the highest consistency between their predicted vault and the actual vault at 6 mo postoperatively.CONCLUSION: The NK and KS formulas of CASIA2 OCT showed the highest consistency between the predicted postoperative vault and the actual vault at 6 mo postoperatively. Both formulas can serve as effective references for ICL model selection.