运用SD-OCT分析头倾斜对视乳头参数重复性的影响

Lilian Hui Li Koh, Muhammad Amir Ismail, Sae Cheong Yap, Elizabeth Poh YingWong, Leonard Wei Leon Yip

2016,9(8):1170-1175    DOI: 10.18240/ijo.2016.08.14

【RecommendedReason】The study evaluated the repeatability of measuring optic nerve head parameters using OCT, as well as the effects of head tilt on the repeatability. The results show that head tilt can cause artifacts in the measurement of retinal nerve fiber layer using Cirrus OCT, the ONH parameters maintain good repeatability.

【推荐理由】该研究运用OCT分析视乳头参数以及头倾斜对检测重复性的影响。结果显示运用Cirrus OCT测量视网膜神经纤维层时，头倾斜可导致伪影，而视乳头参数可维持良好的重复性。

Investigation

Risk factors for diabetic retinopathy in northern Chinese patients with type 2 diabetes mellitus Zhi-PengYan, Jing-Xue Ma

中国北方2型糖尿病患者中糖尿病性视网膜病的危险因素

2016,9(8):1194-1199    DOI:10.18240/ijo.2016.08.17

【RecommendedReason】This retrospective study shows that the presence of diabetic retinopathy in patients with type 2 diabetic mellitus in northern regions of China was associated with the fasting serum glucose concentration,HbA1c level, duration of diabetes and insulin treatment,but the lifestyle habits such as smoking, alcohols, and exercise were not significantly associated with the development of diabetic retinopathy in the present study. The results were clear and discussed interms of the difference of the results of the present study and those of other previous epidemiologic studies.

【推荐理由】此回顾性研究分析了中国北方2型糖尿病患者中糖尿病性视网膜病的发病率与空腹血糖浓度，HbA1c水平，病程，胰岛素治疗时长有关，但其生活习惯如：吸烟，饮酒和运动与糖尿病性视网膜病的发展并无显著关系。结果部分表述清晰并讨论了研究结果与之前流行病研究结果的不同之处。

Review
Nanomedicine in the applicationof uveal melanoma
纳米医学在葡萄膜黑色素瘤中的应用

Shuo You, Jing Luo, Hans E.Grossniklaus, Ma-Ling Gou, Ke Meng, Qing Zhang

2016,9(8):1215-1225   DOI:10.18240/ijo.2016.08.20

【RecommendedReason】Rapid advances in nanomedicine have significantly changed many aspects of nanoparticle application to the eye including areas of diagnosis, imaging and more importantly drug delivery. Then anoparticle-based drug delivery systems has provided a solution to various drug solubility-related problems in ophthalmology treatment. The authors have made a good summary of current advancements of nanomedicine in the field of ophthlamology including uveal melanoma from various aspectsand discuss future directions from an ocular oncology perspective.

【推荐理由】纳米医学的快速发展极大地改变了纳米颗粒应用到眼的许多方面，包括诊断，成像技术，更重要的是给药途径。纳米粒子为基础的给药系统为眼科治疗中各种药物的溶解度相关问题提供了解决方案。作者就目前纳米医学在眼科学领域的应用进展做出了很好的总结，包括葡萄膜黑色素瘤的各个方面并探讨了眼肿瘤学未来的发展方向。

Opinion
Intraocular fine needle aspiration cytology as a diagnostic modality for retinoblastoma

眼内细针吸取细胞学可作为检验视网膜母细胞瘤的方法

Bhavna Chawla, Anand Tomar, SeemaSen, Mandeep S. Bajaj, Seema Kashyap

2016,9(8):1233-1235   DOI:10.18240/ijo.2016.08.23

【RecommendedReason】The role of fine needle aspiration cytology as a diagnostic modality for retinoblastoma has been controversial, mainly due to concerns of tumor dissemination and extra-ocular spread. This study was undertaken to determine the utility and safety of intraocular fine needle aspiration cytology as a supportive diagnostic tool.

【推荐理由】 主要由于对肿瘤扩散和眼外传播的考虑，眼内细针吸取细胞学用来检验视网膜母细胞瘤的方法一直饱受争议。本文研究了眼内细针吸取细胞学作为一个可用的诊断方法用于检验视网膜母细胞瘤的实用性和安全性。

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